{"product_id":"api-general-cure-medication","title":"API General Cure — Broad-Spectrum Antiparasitic Treatment","description":"\u003cp\u003eAPI General Cure is a dual-active antiparasitic powder combining metronidazole and praziquantel — two clinically distinct compounds that target fundamentally different parasite classes. Understanding exactly what each ingredient treats (and what it doesn't) prevents treatment failures and the costly delay of the wrong medication while fish deteriorate.\u003c\/p\u003e\n\n\u003ch3\u003eActive Ingredients \u0026amp; Scientifically Accurate Targets\u003c\/h3\u003e\n\u003ctable style=\"width:100%;border-collapse:collapse;font-size:0.875rem;margin:14px 0;\"\u003e\n\u003cthead\u003e\n\u003ctr style=\"background:rgba(59,130,246,0.08);text-align:left;\"\u003e\n\u003cth style=\"padding:10px 12px;border-bottom:2px solid rgba(128,128,128,0.15);\"\u003eIngredient\u003c\/th\u003e\n\u003cth style=\"padding:10px 12px;border-bottom:2px solid rgba(128,128,128,0.15);\"\u003eConfirmed Targets\u003c\/th\u003e\n\u003cth style=\"padding:10px 12px;border-bottom:2px solid rgba(128,128,128,0.15);\"\u003eMechanism\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"padding:9px 12px;border-bottom:1px solid rgba(128,128,128,0.1);\"\u003e\u003cstrong\u003eMetronidazole\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:9px 12px;border-bottom:1px solid rgba(128,128,128,0.1);\"\u003e\n\u003cem\u003eHexamita\u003c\/em\u003e and \u003cem\u003eSpironucleus\u003c\/em\u003e spp. (hole-in-the-head disease \/ HLLE in cichlids and tangs); internal flagellated protozoa\u003c\/td\u003e\n\u003ctd style=\"padding:9px 12px;border-bottom:1px solid rgba(128,128,128,0.1);\"\u003eDisrupts DNA replication in anaerobic and microaerophilic organisms\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background:rgba(128,128,128,0.03);\"\u003e\n\u003ctd style=\"padding:9px 12px;\"\u003e\u003cstrong\u003ePraziquantel\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"padding:9px 12px;\"\u003eMonogenean flukes: gill flukes (\u003cem\u003eDactylogyrus\u003c\/em\u003e spp.) and skin flukes (\u003cem\u003eGyrodactylus\u003c\/em\u003e spp.); some cestodes (tapeworms); fish lice (\u003cem\u003eArgulus\u003c\/em\u003e spp.)\u003c\/td\u003e\n\u003ctd style=\"padding:9px 12px;\"\u003eDisrupts membrane calcium ion permeability in flatworms, causing paralysis and detachment from host tissue\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\n\u003ch3\u003eWhat General Cure Does NOT Effectively Treat\u003c\/h3\u003e\n\u003cp\u003eNeither metronidazole nor praziquantel is effective against:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFreshwater ich (\u003cem\u003eIchthyophthirius multifiliis\u003c\/em\u003e):\u003c\/strong\u003e requires heat treatment, copper, formalin, or malachite green\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMarine ich (\u003cem\u003eCryptocaryon irritans\u003c\/em\u003e):\u003c\/strong\u003e requires copper (chelated or ionic), chloroquine phosphate, or hyposalinity in a quarantine system\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMarine velvet (\u003cem\u003eAmyloodinium ocellatum\u003c\/em\u003e):\u003c\/strong\u003e a dinoflagellate — requires copper treatment at 2.0–2.5 ppm maintained for 14–21 days minimum\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBacterial infections:\u003c\/strong\u003e use erythromycin (gram-positive) or minocycline (gram-negative)\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eDisease Identification Guide\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHole-in-the-head \/ HLLE:\u003c\/strong\u003e Pitting erosions along the lateral line and head, most common in cichlids (oscars, discus) and tangs. Caused by \u003cem\u003eHexamita\u003c\/em\u003e\/\u003cem\u003eSpironucleus\u003c\/em\u003e. Metronidazole is the first-line treatment.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGill flukes (\u003cem\u003eDactylogyrus\u003c\/em\u003e):\u003c\/strong\u003e Rapid or labored gill movement, gasping at the surface, flashing, mucus on gills, pale or inflamed gill tissue. Praziquantel is first-line.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSkin flukes (\u003cem\u003eGyrodactylus\u003c\/em\u003e):\u003c\/strong\u003e Flashing\/scratching against surfaces, excess mucus, skin redness or erosion, fins clamped. Praziquantel is first-line.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFish lice (\u003cem\u003eArgulus\u003c\/em\u003e):\u003c\/strong\u003e Visible disc-shaped parasites (5–10mm) attached to skin, intense irritation, localized hemorrhage at attachment sites. Praziquantel + manual removal.\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eCompatibility\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSafe for freshwater and saltwater fish\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNot safe\u003c\/strong\u003e for invertebrates (praziquantel is toxic to snails, shrimp, and other inverts — remove before treatment)\u003c\/li\u003e\n\u003cli\u003eSafe for biological filtration at labeled doses\u003c\/li\u003e\n\u003cli\u003eRemove activated carbon before treatment\u003c\/li\u003e\n\u003c\/ul\u003e\n\n\u003ch3\u003eDosing\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e1 packet per 10 gallons directly into aquarium\u003c\/li\u003e\n\u003cli\u003eRepeat after 48 hours\u003c\/li\u003e\n\u003cli\u003eOne package (10 packets) treats up to 100 gallons over a two-dose course\u003c\/li\u003e\n\u003c\/ul\u003e","brand":"YoCamron's Aquatics","offers":[{"title":"10-Pack Powder Packets","offer_id":50095434825965,"sku":"API-GENERALCURE-10CT","price":27.03,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0806\/1032\/8813\/files\/b02527806f9bfe92e4869e470a43384387b4a0a0_png.webp?v=1781976856","url":"https:\/\/yocamronsaquatics.com\/products\/api-general-cure-medication","provider":"YoCamron's Exotics","version":"1.0","type":"link"}